Patents

Inventions, Disclosures and Patents

2018

  • US Patent 9,914,920 - Goodwin, T.J., et al., Alternating Ionic Magnetic Resonance (AIMR) Multiple-Chambered Culture Apparatus
  • US Patent 9,896,681 - Goodwin, T.J. et al., Modifying the genetic regulation of bone and cartilage cells and associated tissue by EMF stimulation fields and uses thereof

2014

  • ‍MSC-24541-2 - Goodwin, T.J.,“Electromagnetic Time Variance Magnetic Fields (TVMF) to Generate and Regrow Cartilage By Non- Invasive Methods”
  • U.S. Patent 8,795,147 - Goodwin, T.J., et al., “Modifying the Genetic Regulation of Bone and Cartilage Cells and Associated Tissue by EMF Stimulation Fields and Uses Thereof”

2013

  • MSC-25633-1 - Goodwin, T.J., et al., “Methods for Culturing Cells in an Alternating Ionic Magnetic Resonance (AIMR) Multiple Chambered Culture Apparatus”
  • MSC-25545-1 - Goodwin, T.J., et al., “AIMR Multiple-Chambered, Apparatus for the Culture of Cells, Tissues, and Organoid Bodies and Methods of Use”

2012

  • U.S. Patent 8,338,114 - Goodwin, T.J., “Engineered human bronchio-epithelial tissue-like assemblies”

2011

  • U.S. Patent 7,972,821 - Goodwin, T.J., et al., “Production of Functional Proteins: Balance of Shear Stress

2010

  • MSC-24949-1 - Goodwin; “Regenerative Physiology and Bio-Engineered Tissue Systems for Development of a Viral Vaccine Platform for Human Vaccine Development

2009

  • U.S. Patent 7,601,114 - Goodwin, T.J., et al., "Apparatus for Enhancing Tissue Repair in Mammals"

2008

  • U.S. Patent 7,456,019 - Goodwin, T. J., et al., "Three-Dimensional Cell to Tissue Development Process"
  • MSC-24541-1 - Goodwin, T.J., "Electromagenetic Time Variance Magnetic Fields (TVMF) To Generate and Regrow Cartilage By a Non- Invasive Method"

2007

  • U.S. Patent 7,198, 947 - Goodwin, T.J., et al., "Production of Functional Proteins: Balance of Shear Stress and Gravity"
  • U.S. Patent 7,179,217 - Goodwin, T.J., et al., "Apparatus for enhancing tissue repair in mammals"

2006

  • MSC-23981-1 PCT - Goodwin, T.J., et al.,"Apparatus for Enhancing Tissue Repair in Mammals"
  • MSC-23983-1 PCT - Goodwin, T.J., et al., "Improved Three-Dimensional Cell to Tissue Development Process"
  • MSC-24164-1 - Goodwin, T.J., "Three- Dimensionally Engineered Normal Human Bronchio- Epithelial Tissue –Like Assemblies: Targets for Human Respiratory Viral Infections"

2005

  • U.S. Patent 6,946,246 - Goodwin, T.J., et al., "Production of Functional Proteins: Balance of Shear Stress and Gravity"
  • MSC-23979 - Goodwin, T.J., et al., "Natively Glycosylated Mammalian Biological Molecules Produced By Electromagnetically Stimulating Living Mammalian Cell"
  • MSC-23980 - Goodwin, T.J., et al., "Interchangable Sleeve For Enhancing Proliferation of Cells in a Rotating Bioreactor"
  • MSC-23981 - Goodwin, T.J., et al., "Apparatus for Enhancing Tissue Repair in Mammals"
  • MSC-23982 - Goodwin, T.J., et al., "Apparatus for Enhancing Proliferation Of Cells in a Small- Scale Cell Culturing Container"
  • MSC-23983 - Goodwin, T.J., et al., "Improved Three-Dimensional Cell to Tissue Development Process"

2004

  • U.S. Patent 6,730, 498 - Goodwin, T.J., et al., "Production of Functional Proteins: Balance of Shear Stress and Gravity "
  • U.S. Patent 6,673,597 - Wolf, D.A. and Goodwin, T.J., "Growth Stimulation of Biological Cells and Tissue by Electromagnetic Fields and Uses Thereof"

2003

  • MSC-23679 - Goodwin, T.J., "Virally Induced Cell Control Via Synthetically Produced Nano- Viruses"
  • MSC-23691-1 - Goodwin, T.J., et al., "Modular Rotating Bioreactor"

2002

  • U.S. Patent, 6,485,963, B1 - Wolf, D.A. and Goodwin, T.J., "Growth Stimulation of Biological Cells and Tissue by Electromagnetic Fields and Uses Thereof"

2000

  • U.S. Patent, 6,117,674 - Goodwin, T.J., et al., "Pathogen Propagation in Cultured Three- Dimensional Tissue Masses"

1999

  • U.S. Patent, 5,962,324 - O’Connor, K.C., Goodwin, T. J., et al., “Three Dimensional Optic Tissue Culture and Process”
  • U.S. Patent, 5,858,783 - Goodwin, T.J., et al., "Production of normal mammalian organ culture using a medium containing MEM-alpha, Leibovitz L-15, glucose galactose fructose"

1998

  • U.S. Patent, 5,851,816 - Goodwin, T.J., Prewett, T.L., Spaulding, G.F., and Wolf, D.A. "Cultured High Fidelity Three-Dimensional Human Urogenital Tract Carcinomas and Process"
  • U.S. Patent 5,846,807 - Goodwin, T.J., "Media compositions for three-dimensional mammalian tissue growth under microgravity culture conditions"
  • MSC-22859-1-PCT and MSC22859-1-CU:Goodwin, T.J., et al., "Production of Functional Proteins: Balance of Shear Stress and Gravity”

1997

  • U.S. Patent 5,637,477Spaulding, G.F., Goodwin, T.J., et al., "Recombinant Protein Production and Insect Cell Culture and Process"
  • U.S. Patent 5,627,021 - Goodwin, T.J., et al., Multi-Cellular, "Three-Dimensional Living Mammalian Tissue"

1996

  • U.S. Patent 5,496,722 - Goodwin, T.J., et al., "Cultured Normal Mammalian Tissue and Process"

1995

  • MSC-22633-1 - Goodwin, T.J., et al., "Electrically Potentiated Growth of Mammalian Neuronal Tissue Facilitated by Rotating Wall Vessel Culture"

1994

  • U.S. Patent 5,308,764 - Goodwin, T.J., et al., "Multi-Cellular Three-Dimensional Living Mammalian Tissue"

1993

  • MSC-2-1 - Goodwin, T.J., et al., "Cultured Normal Mammalian Tissue and Process" U.S.

1992

  • U.S. Patent 5,153,132 - Goodwin, T.J. et al., "Three-Dimensional Coculture Process"
  • MSC-22118-1 - Goodwin, T.J., et al., "A Process for Three-Dimensional Culture of Mammalian Cartilage"
  • MSC-22120-1 - Goodwin, T.J., et al., "A Process for Developing High-Fidelity Three-Dimensional Tumor Models of Human Bladder Carcinoma"
  • MSC-22122-1 - Goodwin, T.J., et al., "Horizontal Rotating Wall Vessel Viral Propagation in In Vitro Human Tissue Models"

1989

  • MSC-21575-1 - Goodwin, T.J., et al., "Biologically Active Factors Produced by Multicellular Cocultivation"
  • MSC-21653-1: GTSF-1 - Goodwin, T.J., et al., "A Serum-Free Medium Designed for the Space Bioreactor System"
Courtesy of NASA